Design and Development of Biodegradable Mg Alloy Implants for Orthopedic applications

PI Details	Co-PI Details
Dr Uma Batra Designation: Professor Department: Metallurgical & Materials Engg. Email ID: umabatra@pec.edu.in	Dr Kamal Designation: Assistant Professor Department: Mechanical Engineering. Email ID: kamaljangra@pec.edu.in

Funding Agency	Project Cost
SERB, DST, New Delhi	77,38,525/- Amount Received till date (in Rs.) 73,82,021/-

Start Date	Completion Date	Status
2017-08-28	2020-09-27	Completed

Abstract

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Two types of bone plates have been designed and developed from ZM21 Mg Alloy for the forearm of an adult- non-perforated bone plate and perforated bone plate. The WEDM (for machining contours of bone plate) and EDD processes (for creating interconnected micro-holes in bone plate) used in the development have been optimized for better surface integrity, low degradation rate and apatite formation rate in biological fluid over the expected bone healing period. A comprehensive study on the mechanical integrity loss (i.e, elastic modulus, compressive strength, fatigue strength, bending strength and fracture toughness) of perforated and non-perforated bone plates at regular intervals during complete degradation test period. Correlation between processing parameters (WEDM & EDD) have been established with surface characteristics, degradation rate, apatite formation rate and mechanical integrity of ZM 21 Mg-alloy to predefine the life span of bone plate.

Manpower Sanctioned/Hired	Manpower Trained
JRF (Nos): 01	Ph.D Produced: 03 M.Tech. Produced: 02 Technical Staff: 10

Equipment Sanctioned/Procured

Name of Equipment	Make & Model	Year of Purchase	Cost	Salient Features of Equipment	Condition (Working /Not Working)
CNC Wire EDM setup with accessories	Ecocut, Electronica India Ltd.	2018	24,95,700/-	5-axis CNC Wire EDM	Working
Computerized Universal Testing Machine	HEICO,	2018	25,20,000/-	Fatigue Rated Machine 25KN	Working
Stereo Zoom Microscope	Carl Zeiss, Stemi Trino 305	2018	2,28,000/-	Magnification: 4X	Working

Publications

List of SCI Publications under Project

Authors Name	Title of Paper	Journal Name	Volume	Page No.	Year
Kamal Kumar, RS Gill, Uma Batra	Challenges and Opportunities for biodegradable Magnesium Alloy Implants	Materials Technology https://doi.org/10.1080/10667857.2017.1377973	Vol. 33(2)	153-172	2018
Neeraj Ahuja, Kamal Kumar, Uma Batra, and Sudhir Kumar Garg	Fabrication of Biodegradable Mg Alloy Bone Scaffold Through Electrical Discharge µ-Drilling Route	Advances in Manufacturing II https://doi.org/10.1007/978-3-030-16943-5_13	Vol. 4	145–155	2019
Neeraj Ahuja, Uma Batra, and Kamal Kumar	Experimental Investigation and Optimization of Wire Electrical Discharge Machining for Surface Characteristics and Corrosion Rate of BiodegradableMg Alloy	Journal of Materials Engineering and Performance https://doi.org/10.1007/s11665-020-04905-8	Volume 29(6)	4117–4129	2020
Neeraj Ahuja, Uma Batra, Kamal Kumar	Multicharacteristics optimization of electrical discharge micro hole drilling in Mg alloy using hybrid approach of GRA–regression–PSO DOI: 10.1108/GS-03-2020-0029	Grey Systems: Theory and Application	Volume 11(1)	136-151	2020
Navdeep Singh, Uma Batra, Kamal Kumar, Anil Mahapatro	Investigating TiO2–HA–PCL hybrid coating as an efficient corrosion resistant barrier of ZM21 Mg alloy https://doi.org/10.1016/j.jma.2020.08.003	Journal of Magnesium and alloys			2020
RS Gill, Uma Batra, Kamal Kumar	Surface characteristics and corrosion behavior of WEDMed processed Mg-4Zn alloy 10.1007/s11665-021-05525-6	Journal of Materials Engineering and Performance			2021

List of Conference Publication Published in Proceedings under Project

Authors Name	Title of Paper	Name of Conference	Place	National/ International	Page No.	Year
Ahuja, N., Kumar, K., Batra, U. and Garg, S.K.	Fabrication of Biodegradable Mg Alloy Bone Scaffold Through Electrical Discharge µ-Drilling Route. http://dx.doi.org/10.1007/978-3-030-16943-5_13	International Scientific-Technical Conference MANUFACTURING, (Published in Advances in Manufacturing II)	POZNAN, Poland	International	145-155, Springer, Cham)	May, 2019

Authors Name

Title of Paper

Name of Conference

Place

National/

International

Page No.

Year

Ahuja, N., Kumar, K., Batra, U. and Garg, S.K.

Fabrication of Biodegradable Mg Alloy Bone Scaffold Through Electrical Discharge µ-Drilling Route.
http://dx.doi.org/10.1007/978-3-030-16943-5_13

International Scientific-Technical Conference MANUFACTURING, (Published in Advances in Manufacturing II)

POZNAN, Poland

International

145-155, Springer, Cham)

May, 2019

Output/Outcome of the Project

Output/Outcome of the project

Six SCI Publications
No. of Ph.D. produced: 03
Other Technical Personnel trained: 10